NLRC5 is an important regulator in antigen presentation and inflammation, and its dysregulation promotes tumor progression.In melanoma, the impact of NLRC5 expression on molecular phenotype, clinical characteristics, and tumor features is largely unknown.In the present study, public datasets from the Cancer Cell Line Encyclopedia (CCLE), Gene Expre
Dinoflagellates are known to possess a highly aberrant nucleus—the so-called dinokaryon—that exhibits a multitude of exceptional biological features.These include: (1) Permanently condensed chromosomes; (2) DNA in a cholesteric liquid crystalline state, (3) extremely large DNA content (up to 200 pg); and, perhaps most strikingly, (4) a
The effect of ethynylene spacers on the bandgap of alternating polymers, comprising 4,7-linked benzothiadiazole units and 2,7-linked fluorene, 2,7-linked carbazole or 2,6-linked anthracene repeat units has been investigated.The three novel polymers PFDEBT, PCDEBT and PPADEBT were prepared via the Sonogashira coupling Abrasive reaction.The optical,
Abstract Background Studying reproductive trait allometries can help to understand Klassy Cowgirl optimal male investment strategies under sexual selection.In promiscuous mating systems, studies across several taxa suggest that testes allometry is usually positive, presumably due to strong selection on sperm numbers through intense sperm competitio
The canonical function of lentiviral Vif proteins is to counteract the mutagenic potential of APOBEC3 antiviral restriction factors.However, recent studies have discovered that Vif proteins from diverse HIV-1 and simian immunodeficiency virus (SIV) isolates degrade cellular B56 phosphoregulators to remodel the host phosphoproteome and induce G2/M c